Blocking a surprising master regulator of immunity eradicates liver tumors in mice
Stanford Medicine
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Eradicating liver tumors
Liver Cancer April 24, 2025
By Krista Conger
“Cold” tumors are resistant to common immunotherapies. Stanford Medicine researchers have uncovered a master regulator that can be manipulated to prevent tumor growth in mice.
Editor's note: Above left: In “cold” immunotherapy-unresponsive tumors, tumor cells make EPO, which binds to receptors on macrophages. By removing or blocking macrophage EPO receptors, scientists can make tu...
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