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Blocking a surprising master regulator of immunity eradicates liver tumors in mice

Stanford Medicine News Center Latest Articles Eradicating liver tumors Liver Cancer April 24, 2025 By Krista Conger “Cold” tumors are resistant to common immunotherapies. Stanford Medicine researchers have uncovered a master regulator that can be manipulated to prevent tumor growth in mice. Editor's note: Above left: In “cold” immunotherapy-unresponsive tumors, tumor cells make EPO, which binds to receptors on macrophages. By removing or blocking macrophage EPO receptors, scientists can make tu...

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